FLOATING DRUG DELIVERY: AN EFFECTIVE TREATMENT FOR DYSMENORRHEA

Registration ID: IJNRD_185325

Published ID: IJNRD2301024

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Ekta Wadbudhe, Zohra Firdous, Nitin Padole, Jagdish Baheti

Keywords: Floating tablet, Dysmenorrhea, Polymer

Abstract Dysmenorrhea is a medical term that describes the word ‘‘menstrual pain”, women suffer from primary and secondary dysmenorrhea. Non-steroidal anti-inflammatory medicines such as hormonal drugs are used for the treatment of dysmenorrhea, and diagnostic tests are available for dysmenorrhea such as ultrasonography, laparoscopy, and magnetic resonance imaging (MRI). Non-steroidal anti-inflammatory drugs help in reducing pain and continue to be the first-line treatment recommended for menstrual discomfort. This study evaluated various excipients for their floating behavior and in-vitro profiles of floating tablets. Purpose of floating on this review by reducing contractions of the smooth muscles of the abdomen. This review focuses on methods for the preparation of floating tablets, the following techniques were reported as direct compression, melt granulation, melt solidification, spray drying, and wet granulation. Pre-compression parameters like angle of repose, bulk density, and tapped density, also evaluation parameters such as drug content, Differential Scanning Calorimetry (DSC), tablet thickness, friability, weight variation, in-vitro buoyancy, index swelling, and drug release were reported. This review gives an idea about the polymer which are suitable and compatible with the drug for the preparation of floating tablets and the effect of polymer, gas forming agent. A review concludes that a floating medicine delivery device is the most effective treatment for dysmenorrhea. everyday activities are delayed by menstrual symptoms associated with dysmenorrhea, such as cramping and stomach ache. The floating drug delivery system is one of the best drug administration methods that can preserve a medication for a long period of time and increase its therapeutic efficacy. The first-line treatment for menstrual pain is still non-steroidal anti-inflammatory drugs. So floating drug delivery can be a better alternative for previously existing treatments and dosage forms.

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Ekta Wadbudhe, Zohra Firdous, Nitin Padole, & Jagdish Baheti (January-2023). FLOATING DRUG DELIVERY: AN EFFECTIVE TREATMENT FOR DYSMENORRHEA. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(1), a191-a204. https://ijnrd.org/papers/IJNRD2301024.pdf

Volume 8 Issue 1, January-2023

Pages : a191-a204

Paper Reg. ID: IJNRD_185325

Published Paper Id: IJNRD2301024

Downloads: 000122254

Research Area: Health Science 

Author Type: Indian Author

Country: katol,nagpur, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2301024.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2301024

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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