Paper Title
FORMULATION, DEVELOPMENT AND EVALUATION FOR TRANSDERMAL DRUG DELIVERY OF AN ANTIDIABETIC DRUG CANAGLIFLOZIN
Article Identifiers
Authors
SIDDHARTH MISHRA , AMIT SAHU , KAVITA R LOKSH
Keywords
: Transdermal Patches,Plasma Concentration,Solubility,Moistur Content,Pharmacological Properties
Abstract
Transdermal drug delivery system (TDDS) is novel approach which mainly design to sustain the release and improve the bioavailability of drug and patient compliance. Among the various types of transdermal patches, matrix dispersion type systems disperse the drug in the solvent along with the polymers and solvent is allowed to evaporate forming a homogeneous drug-polymer matrix. A medicated transdermal patch system is one of the novel drug delivery in which it is placed on the skin surface to deliver the specific dose of medicament via skin to the blood circulation through the skin and into the bloodstream.Canagliflozin (CFZ) belongs to a novel class of sodium glucose co-transporter (SGLT II) inhibitors and has been widely used for the management of type 2 diabetes mellitus (T2DM) through insulin independent mechanism. SGLT II is a low capacity/high affinity Na + /K+ co-transporter predominantly located in proximal convoluted tubules (PCT) of kidneys which prevents reabsorption of glucose and thereby stimulating glucose excretion in the urine. The aim of present work to develop transdermal patches of anti-diabetic drug for improves the bioavailability of drug Canagliflozin.
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How To Cite (APA)
SIDDHARTH MISHRA, AMIT SAHU, & KAVITA R LOKSH (December-2022). FORMULATION, DEVELOPMENT AND EVALUATION FOR TRANSDERMAL DRUG DELIVERY OF AN ANTIDIABETIC DRUG CANAGLIFLOZIN. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(12), d90-d106. https://ijnrd.org/papers/IJNRD2212309.pdf
Issue
Volume 7 Issue 12, December-2022
Pages : d90-d106
Other Publication Details
Paper Reg. ID: IJNRD_185065
Published Paper Id: IJNRD2212309
Downloads: 000121980
Research Area: Pharmacy
Country: BHOPAL, Madhya Pradesh, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2212309.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2212309
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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