A Comparitive Analysis and Study of HEART and TIMI Scoring with Use of High Sensitivity Troponin I in patients with Acute Chest Pain

Registration ID: IJNRD_185294

Published ID: IJNRD2212266

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Dr. Varun S , Dr. Suraj Horakeri , Dr. KhatijaJhumkawala , Dr.D.B Bhusare

Keywords: Chest pain, Major Adverse Cardiac Events (MACE), Heart stands for {History, Electrocardiogram, Age, Risk factors, Initial troponin}, TIMI {Thrombolysis in Myocardial infarction}, GRACE {Global registry of acute coronary events}.

ABSTRACT Introduction Chest pain is the most common initial symptom in patients diagnosed with coronary artery disease. Therefore, distinguishing Acute coronary syndrome from other cardiac and non-cardiac disease is crucial to identify patients who are at high and low risk of developing major adverse cardiac events (MACE) in order to optimally allocate Emergency department (ED) and hospital resources and to promote efficient and effective care. The study was planned to compare the performances of risk scores HEART and TIMI for the prediction of major adverse cardiac events (MACE) in acute chest pain patients presenting to Emergency department. Aims 1.To study comparative accuracy of HEART, TIMI for the prediction of major adverse cardiac events (MACE)in acute chest pain patients presenting to emergency department. 2.To study the role of high sensitivity cardiac troponins as marker in HEART scoring system in emergency department Setting And Design: A prospective observational study in patients presented with chest pain of acute onset at the emergency department of our hospital Material And Method: The study was carried out at MGM medical college, Kamothe, Navi Mumbai which included 100 patients presented to ED with acute chest pain. The patients were evaluated by data on age, gender, presenting history, physical examination, electrocardiography, laboratory results and risk factors. The end point in our study was major adverse cardiac events (MACE) within 6 weeks after the initial ED presentation Results And Conclusion Mean age of the study cases was 63.32 years and 68% cases being over 60 years of age and Male predominance was seen in the study cases with 69% males to 31% females. Major risk factors seen in the study cases was hypertension (61%), dyslipidemia (33%), diabetes (31%), history of smoking (29%) and obesity (21%). Family history of CAD was given by 13% and history of IHD was given by 11% cases. The study shows incidence of MACE (UA, NSTEMI, STEMI, PCI, CABG, stenosis) managed conservatively, cardiovascular death with unknown cause among cases with acute chest pain was 21% and incidence of mortality was 7% in acute chest pain cases. Sensitivity and specificity of TIMI score (>0) for prediction of MACE was 90.5% and 68.4% with overall accuracy as 73%. Sensitivity and specificity of HEART score (>3) for prediction of MACE was 95.2% and 72.2% with overall accuracy as 77%. Sensitivity and specificity of high Hs troponin I for prediction of MACE event was 76.2% and 70.9% with overall accuracy as 72%.

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Dr. Varun S, Dr. Suraj Horakeri, Dr. KhatijaJhumkawala, & Dr.D.B Bhusare (December-2022). A Comparitive Analysis and Study of HEART and TIMI Scoring with Use of High Sensitivity Troponin I in patients with Acute Chest Pain. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(12), c525-c531. https://ijnrd.org/papers/IJNRD2212266.pdf

Volume 7 Issue 12, December-2022

Pages : c525-c531

Paper Reg. ID: IJNRD_185294

Published Paper Id: IJNRD2212266

Downloads: 000121982

Research Area: Medical Science

Country: Navi Mumbai, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2212266.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2212266

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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