Paper Title
Species Distribution And Antifungal Susceptibility Of Candida Species In Blood Culture Isolated From A Tertiary Care Hospital In Odisha: Our Experience
Article Identifiers
Authors
Dr. Nabanita Chakraborti , Dr. Pragyan Paramita Jena , Prof.Dr.Kundan Kumar Sahu
Keywords
candidaemia, Blood stream infections, Fungemia, nosocromial, emerging fungal pathogens.
Abstract
Blood stream infections caused by species of Candida may occur both in the community and in the hospital admitted patients and are the cause of significant morbidity ,mortality and health care cost.Difficulty in detection of fungus in clinical specimen is an important cause of less studies on fungal blood stream infections than bacterial.The present study was done with the aim of to determine the species distribution of Candida in blood stream infections and antifungal susceptibility patterns of different species of candida isolated from blood samples collected from patients admitted in different wards of the SUM hospital, Odisha and in patients attending OPD of the same hospital during the study period(2 years from January 2020 to December 2021). Species-level identification and antifungal susceptibility of these fungal isolates were performed using a fully automated VITEK 2 machine.Of the 2746 blood samples obtained from OPD, IPD and ICU during the last 2 years, a total of 166 (6.04%) blood samples were positive for yeast. 115 (69.27%) were from the intensive care unit (ICU), 43 (25.9%) from other wards and 8 (4.81%) were from OPD. Most common species isolated was Candida auris in patients with different clinical diagnosis, C.auris 66 (40.74%), C.parapsilosis29 (18%), C.tropicalis20 (12.34%), C. albicans 18 (11.11%), C. dobushaemulonii 13 (802%), C.glabrata 6 (3.70%), C.pelliculosa 3 (1.85%), C.famata2 (1.23%), C.lipolytica2 (1.23%), C.gullienmondii 2 (1.23%), C.kefyr 1 (0.6%). Male affected 61.44% and female affected 38.55%. Automated culture system (VITEK) must include C.auris. Additionally, hospitals should update their own protocols for antifungal drug use by evaluating yeast species growing in their own units. Consultation with an infectious disease specialist should be part of the protocol when treating candidaemia.
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How To Cite (APA)
Dr. Nabanita Chakraborti, Dr. Pragyan Paramita Jena, & Prof.Dr.Kundan Kumar Sahu (December-2022). Species Distribution And Antifungal Susceptibility Of Candida Species In Blood Culture Isolated From A Tertiary Care Hospital In Odisha: Our Experience. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(12), a467-a475. https://ijnrd.org/papers/IJNRD2212066.pdf
Issue
Volume 7 Issue 12, December-2022
Pages : a467-a475
Other Publication Details
Paper Reg. ID: IJNRD_184690
Published Paper Id: IJNRD2212066
Downloads: 000121986
Research Area: Medical Science
Country: Bhubaneswar, Odisha, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2212066.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2212066
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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