Species Distribution And Antifungal Susceptibility Of Candida Species In Blood Culture Isolated From A Tertiary Care Hospital In Odisha: Our Experience

Species Distribution And Antifungal Susceptibility Of Candida Species In Blood Culture Isolated From A Tertiary Care Hospital In Odisha: Our Experience

Registration ID: IJNRD_184690

Published ID: IJNRD2212066

DOI: Click Here to Get

Dr. Nabanita Chakraborti , Dr. Pragyan Paramita Jena , Prof.Dr.Kundan Kumar Sahu

candidaemia, Blood stream infections, Fungemia, nosocromial, emerging fungal pathogens.

Blood stream infections caused by species of Candida may occur both in the community and in the hospital admitted patients and are the cause of significant morbidity ,mortality and health care cost.Difficulty in detection of fungus in clinical specimen is an important cause of less studies on fungal blood stream infections than bacterial.The present study was done with the aim of to determine the species distribution of Candida in blood stream infections and antifungal susceptibility patterns of different species of candida isolated from blood samples collected from patients admitted in different wards of the SUM hospital, Odisha and in patients attending OPD of the same hospital during the study period(2 years from January 2020 to December 2021). Species-level identification and antifungal susceptibility of these fungal isolates were performed using a fully automated VITEK 2 machine.Of the 2746 blood samples obtained from OPD, IPD and ICU during the last 2 years, a total of 166 (6.04%) blood samples were positive for yeast. 115 (69.27%) were from the intensive care unit (ICU), 43 (25.9%) from other wards and 8 (4.81%) were from OPD. Most common species isolated was Candida auris in patients with different clinical diagnosis, C.auris 66 (40.74%), C.parapsilosis29 (18%), C.tropicalis20 (12.34%), C. albicans 18 (11.11%), C. dobushaemulonii 13 (802%), C.glabrata 6 (3.70%), C.pelliculosa 3 (1.85%), C.famata2 (1.23%), C.lipolytica2 (1.23%), C.gullienmondii 2 (1.23%), C.kefyr 1 (0.6%). Male affected 61.44% and female affected 38.55%. Automated culture system (VITEK) must include C.auris. Additionally, hospitals should update their own protocols for antifungal drug use by evaluating yeast species growing in their own units. Consultation with an infectious disease specialist should be part of the protocol when treating candidaemia.

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"Species Distribution And Antifungal Susceptibility Of Candida Species In Blood Culture Isolated From A Tertiary Care Hospital In Odisha: Our Experience", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.7, Issue 12, page no.a467-a475, December-2022, Available :https://ijnrd.org/papers/IJNRD2212066.pdf

Volume 7 Issue 12, December-2022

Pages : a467-a475

Paper Reg. ID: IJNRD_184690

Published Paper Id: IJNRD2212066

Downloads: 000121156

Research Area: Medical Science

Country: Bhubaneswar, Odisha, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2212066.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2212066

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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