INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Migraine being a very serious issue unaddressed by most of the patient assuming it as a normal headache is leading to the chronic conditions of the individual. These conditions are increasing across the globe and the awareness within our communities need to be taken care of as it is a complex neurological disorder which is related to several CNS systems such as sensorics and motoric, cognitive, affective and autonomous systems is categorised as migraine. The calcitonin gene related peptide receptor (CGRP) is the receptor of calcitonin family which also includes amylin, adrenomedullin and calcitonin receptors. Among these CGRP receptors play a major role in migraine but its exact role is yet to be analysed. Already existing treatments such as Triptans showed high agonist activity at serotonin receptors but not every triptan has the affinity at the receptors. However, Patients mentioned that the response of the body towards this triptans is poor and others may have headache recurrence and chest syndromes. Aimovig a miracle drug came to existence showing its effectiveness more appropriately and significantly by pre-clinical and clinical studies proving to show the statistical analysis of 70mg of aimovig shows p value of <0.001 and of 140mg p value of <0.001 which are similar. The secondary outcomes of the results are the % of participants with at least 50% of reduction in monthly migraine days (which differ from each patient). Aimovig is proving to show less adverse events associated irrespective of the other factors and showed more effectiveness in reducing the migraine condition and improving the quality of life of the patients.
Keywords:
Aimovig, calcitonin gene related peptide receptor, headache, Migraine.
Cite Article:
"Aimovig serving as a miracle drug for chronic migraine – A clinical Review", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 11, page no.c450-c456, November-2022, Available :http://www.ijnrd.org/papers/IJNRD2211257.pdf
Downloads:
000118743
ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Facebook Twitter Instagram LinkedIn