Paper Title
COMPARATIVE STUDY OF ANTIMICROBIAL ACTIVITIES OF SOME BIS-ISOXAZOLINES AND BIS-ISOXAZOLES
Article Identifiers
Authors
Dr. Jyoti Shegokar
Keywords
Bis-isoxazolines, Bis-isoxazoles, hydroxylamine hydrochloride, antimicrobial activity. Introduction
Abstract
Abstract A Series of substituted 1,1–{bis-[3-hydroxy-4-(3Ι,4Ι-disubstitutedphenyl)-isoxazolin-3-yl]-oxyphenyl}-methanes – (IV) and 1,1–{bis-[3-hydroxy-4-(3Ι,4Ι -disubstitutedphenyl)-isoxazol-3-yl] oxyphenyl}-methanes (VII) have been synthesized by condensation of 1,1–{bis-[3-hydroxy-4-(3Ι,4Ι-disubstituted-phenyl)-prop-2-ene-1-one]-oxyphenyl}-methanes- (II) and 1,1-{bis-[3-hydroxy-4-3-(3 Ι,4 Ι -disubstitutedphenyl)–propane-2-1,3-dione]-oxyphenyl} methanes- (VIB) with hydroxylamine hydrochloride respectively. The compounds were characterized by IR and 1H NMR spectral studies. All the compounds were evaluated for their antibacterial and antifungal activities. The organisms screened were Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Staphylococcus epidermisdis, Salmonella Abony, Candida albicans and Saccharomyces Cerevisia. Comparative study of these synthesized bis-Isoxazolines and bis-Isoxazoles have been carried out in this paper.
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Dr. Jyoti Shegokar (November-2022). COMPARATIVE STUDY OF ANTIMICROBIAL ACTIVITIES OF SOME BIS-ISOXAZOLINES AND BIS-ISOXAZOLES . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(11), c317-c324. https://ijnrd.org/papers/IJNRD2211241.pdf
Issue
Volume 7 Issue 11, November-2022
Pages : c317-c324
Other Publication Details
Paper Reg. ID: IJNRD_184355
Published Paper Id: IJNRD2211241
Downloads: 000121979
Research Area: Chemistry
Country: Akola, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2211241.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2211241
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