Prodrugs : An approach to improve the effectiveness and properties of the drug

Prodrugs : An approach to improve the effectiveness and properties of the drug

Registration ID: IJNRD_184361

Published ID: IJNRD2211237

DOI: Click Here to Get

Manish S. Junagade , Anju Goyal

drugs, undesirable properties. side effects, prodrug design,mutual prodrugs

A clinically used drug may have limitations in practice because of undesirable side effects, poor solubility, poor bioavailability, short duration of action, first-pass effect, poor absorption & adverse effects. To overcome such undesirable properties, one of the approaches to convert the existing molecule to a more efficient molecule is prodrug design. Prodrug can be synthesized to impart desirable properties in it. Prodrugs are inert in nature but after administration they get activated through metabolic reactions invivo. The activated form then shows the pharmacological activity. Properties of a drug can be improved by selecting proper carrier moiety during its design.The design of mutual prodrug is very fruitful in the area of research & has given successful results in increasing the clinical & therapeutic effectiveness of the drugs.In present article such prodrugs prepared of drugs from various classes are discussed.

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" Prodrugs : An approach to improve the effectiveness and properties of the drug", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.7, Issue 11, page no.c273-c287, November-2022, Available :https://ijnrd.org/papers/IJNRD2211237.pdf

Volume 7 Issue 11, November-2022

Pages : c273-c287

Paper Reg. ID: IJNRD_184361

Published Paper Id: IJNRD2211237

Downloads: 000121161

Research Area: Pharmacy

Country: Udaipur, Rajasthan, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2211237.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2211237

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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