Paper Title
Prodrugs : An approach to improve the effectiveness and properties of the drug
Article Identifiers
Authors
Manish S. Junagade , Anju Goyal
Keywords
drugs, undesirable properties. side effects, prodrug design,mutual prodrugs
Abstract
A clinically used drug may have limitations in practice because of undesirable side effects, poor solubility, poor bioavailability, short duration of action, first-pass effect, poor absorption & adverse effects. To overcome such undesirable properties, one of the approaches to convert the existing molecule to a more efficient molecule is prodrug design. Prodrug can be synthesized to impart desirable properties in it. Prodrugs are inert in nature but after administration they get activated through metabolic reactions invivo. The activated form then shows the pharmacological activity. Properties of a drug can be improved by selecting proper carrier moiety during its design.The design of mutual prodrug is very fruitful in the area of research & has given successful results in increasing the clinical & therapeutic effectiveness of the drugs.In present article such prodrugs prepared of drugs from various classes are discussed.
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How To Cite (APA)
Manish S. Junagade & Anju Goyal (November-2022). Prodrugs : An approach to improve the effectiveness and properties of the drug. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(11), c273-c287. https://ijnrd.org/papers/IJNRD2211237.pdf
Issue
Volume 7 Issue 11, November-2022
Pages : c273-c287
Other Publication Details
Paper Reg. ID: IJNRD_184361
Published Paper Id: IJNRD2211237
Downloads: 000121981
Research Area: Pharmacy
Country: Udaipur, Rajasthan, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2211237.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2211237
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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