Paper Title
IN-VITRO STUDY THE ANTIMICROBIAL ACTIVITY OF AN ALCOHOLIC EXTRACT OF VITEX NEGUNDO LINN. BY DISC DIFFUSION METHOD
Article Identifiers
Authors
Dr. Vikas Gawali , Ganesh Kardile , Suvarna Kothule , Dr. Yogesh Bafna
Keywords
Antimicrobial activity, Vitex negundo Linn. Disk Diffusion Method, S. aureus, E. coli.
Abstract
In the past decade, the antimicrobial properties of plant extracts have gotten more attention. The current study employs Mueller-Hilton agar-based assays to evaluate several types of leaves of Vitex negundo Linn. (Nirgundi) for in vitro antibacterial activity against gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacteria (disk diffusion method).The results suggested that the ethanolic extract of Vitex negundo showed zones of inhibition of 12.19 ± 0.445 mm, 17.23 ± 0.761 mm and 21.03± 0.559 mm against Staphylococcus aureus and 09.21± 0.357, 13.88 ± 0.652 and 18.48 ± 0.340 against E coli at concentrations of 100 g/mL, 200 g/mL and 400 g/mL, respectively. The percentage zone of inhibition of alcoholic extract of Vitex negundo 400 g/mL showed 74.93% and 68.95% against S. aureus and E coli, which is significant (P < 0.01) as compared to the positive control group. The aq. extract of Vitex negundo 400 g/mL inhibited S. aureus and E. coli with a significant (P< 0.01) zone of inhibition of 64.22 percent and 52.13 percent, respectively. The findings revealed that the ethanolic extracts of Vitex negundo Linn. Leaf showed a more prominent antibacterial effect than the aqueous extract against S. aureus and E. coli. Respectively.
Downloads
How To Cite (APA)
Dr. Vikas Gawali, Ganesh Kardile, Suvarna Kothule, & Dr. Yogesh Bafna (November-2022). IN-VITRO STUDY THE ANTIMICROBIAL ACTIVITY OF AN ALCOHOLIC EXTRACT OF VITEX NEGUNDO LINN. BY DISC DIFFUSION METHOD. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(11), c220-c226. https://ijnrd.org/papers/IJNRD2211229.pdf
Issue
Volume 7 Issue 11, November-2022
Pages : c220-c226
Other Publication Details
Paper Reg. ID: IJNRD_184297
Published Paper Id: IJNRD2211229
Downloads: 000121986
Research Area: Pharmacy
Country: Ahmednagar, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2211229.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2211229
About Publisher
Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG
Licence
This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
Publication Timeline
Article Preview: View Full Paper
Call For Paper
IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.
The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse fields. Its goal is to promote global scientific information exchange among researchers, developers, engineers, academicians, and practitioners. IJNRD serves as a platform where educators and professionals can share research evidence, models of best practice, and innovative ideas, contributing to academic growth and industry relevance.
Indexing Coverage includes Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many more recognized academic repositories.
How to submit the paper?
By Our website
Click Here to Submit Paper Online
Important Dates for Current issue
Paper Submission Open For: October 2025
Current Issue: Volume 10 | Issue 10 | October 2025
Impact Factor: 8.76
Last Date for Paper Submission: Till 31-Oct-2025
Notification of Review Result: Within 1-2 Days after Submitting paper.
Publication of Paper: Within 01-02 Days after Submititng documents.
Frequency: Monthly (12 issue Annually).
Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.
Subject Category: Research Area
Call for Paper: More Details
