Oral Insulin Delivery by Utilizing Nanotechnology

Oral Insulin Delivery by Utilizing Nanotechnology

Registration ID: IJNRD_183906

Published ID: IJNRD2211067

DOI: Click Here to Get

Hemant Arvind Narule , Shaikh Habiburrahman , Mohammed Sufiyan , Kuldeep Sanjay Wagh , Gajanan Daphal

: oral insulin, absorption barrier, nanodrug delivery system, bioavailability

Abstract: Diabetes is a chronic metabolic condition defined by a shortage of insulin in the body, resulting in blood glucose regulation failure. Diabetes patients typically require frequent insulin injections to maintain normal blood glucose levels, which can be an unpleasant method of administration. Long-term medication injection places a significant physical and psychological strain on diabetes patients. The creation of oral insulin formulations is currently a hot and difficult topic in the world of medicine and pharmacy in order to increase patients' adaptability to insulin use and lessen the pain caused by injection. Thus, oral insulin administration is a promising and convenient means of relieving patients. However, because insulin is a peptide medication, it is easily destroyed by stomach enzymes. Furthermore, insulin has a high hydrophilicity, a big molecular weight, and a very limited oral bioavailability. To address these issues in clinical practice, oral insulin delivery nano-systems were devised and built using a rational combination of various nanomaterials and nanotechnology. Such oral nano-systems offer the benefits of high flexibility, small size, simple processing, long-lasting pharmacological activity, and drug controlled-release, which can effectively improve insulin oral bioavailability and efficacy. This study highlights the basic principles and recent accomplishments in oral insulin delivery nano-systems, including the physiological absorption barrier of oral insulin and the development of materials to nanostructures for oral insulin delivery nano-systems.

Published Paper   E-Certificate

"Oral Insulin Delivery by Utilizing Nanotechnology", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.7, Issue 11, page no.a606-a621, November-2022, Available :https://ijnrd.org/papers/IJNRD2211067.pdf

Volume 7 Issue 11, November-2022

Pages : a606-a621

Paper Reg. ID: IJNRD_183906

Published Paper Id: IJNRD2211067

Downloads: 000121114

Research Area: Pharmacy

Country: Chandrapur, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2211067.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2211067

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

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