A REVIEW ON ANTI-OXIDANT AND ANTIHYPERLIPIDEMIC ACTIVITES OF CAESALPINIA SAPPAN BARK.

A REVIEW ON ANTI-OXIDANT AND ANTIHYPERLIPIDEMIC ACTIVITES OF CAESALPINIA SAPPAN BARK.

Registration ID: IJNRD_183490

Published ID: IJNRD2210088

DOI: Click Here to Get

A.M. Krupanidhi , Prabha hulatti , Sregiri Hiremath , Geetha A.M. , B Naipunya

Caesalpinia sappan, flavonoids, Anti-oxidant, Anti- hyperlipidaemic

In many occasions, human beings are exposed to various environmental, occupational and xenobiotics challenges due to modern life styles. Enormous free radicals are generated during exposure to suck stressful conditions. In addition to this, the process of metabolism and excretion of xenobiotics may also generate free radicals. Thus, generated free radicals may produce beneficial oxidation thereby releases energy. However, the excessive free radicals may attack DNA, cell membranes and other cellular components and destroy them. The inbuilt free radicals scavenging system like glutathione, SOD, catalase etc., are involved in scavenging of the excessive free radicals. But the continuous exposure to the stressful conditions may be overpowering the inbuilt scavenging capacity of the cells leading to cellular destruction. The various free radicals that are released in to the body are superoxide anion (O.2), NO radical NOO., OH. And H2O2 radical. Thus, released free radicals react with the membrane polyunsaturated lipids and oxidize them to lipid peroxides. This lipid peroxidation damage membrane protein as well as the lipids and thereby the integrity of membrane is lost. Therefore, it is considered that the extent of lipid peroxidation is directly proportional to cell damage. In addition, the free radicals may also attack DNA and causes tissue damage. Hyperlipidaemia is the greatest risk factor contributing to atherosclerosis & occurrence of coronary heart disease & cerebrovascular accidents. Hence hypolipidemic drugs are extensively used as prophylactic agents to prevent such atherosclerosis induced disorders. plants have been documented to have significant hypolipidemic actions. Based on these phytoconstituents the present is focused on review on antioxidant and antihyperlipidemic activities of Caesalpinia sappan bark.

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"A REVIEW ON ANTI-OXIDANT AND ANTIHYPERLIPIDEMIC ACTIVITES OF CAESALPINIA SAPPAN BARK.", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.7, Issue 10, page no.715-723, October-2022, Available :https://ijnrd.org/papers/IJNRD2210088.pdf

Volume 7 Issue 10, October-2022

Pages : 715-723

Paper Reg. ID: IJNRD_183490

Published Paper Id: IJNRD2210088

Downloads: 000121124

Research Area: Pharmacy

Country: davanagere, karnataka, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2210088.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2210088

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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