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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | A REVIEW ON ANTI-OXIDANT AND ANTIHYPERLIPIDEMIC ACTIVITES OF CAESALPINIA SAPPAN BARK. |
| Authors Name: | A.M. Krupanidhi , Prabha hulatti , Sregiri Hiremath , Geetha A.M. , B Naipunya |
| Download E-Certificate: | Download |
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IJNRD_183490
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| Published Paper Id: | IJNRD2210088 |
| Published In: | Volume 7 Issue 10, October-2022 |
| DOI: | |
| Abstract: | In many occasions, human beings are exposed to various environmental, occupational and xenobiotics challenges due to modern life styles. Enormous free radicals are generated during exposure to suck stressful conditions. In addition to this, the process of metabolism and excretion of xenobiotics may also generate free radicals. Thus, generated free radicals may produce beneficial oxidation thereby releases energy. However, the excessive free radicals may attack DNA, cell membranes and other cellular components and destroy them. The inbuilt free radicals scavenging system like glutathione, SOD, catalase etc., are involved in scavenging of the excessive free radicals. But the continuous exposure to the stressful conditions may be overpowering the inbuilt scavenging capacity of the cells leading to cellular destruction. The various free radicals that are released in to the body are superoxide anion (O.2), NO radical NOO., OH. And H2O2 radical. Thus, released free radicals react with the membrane polyunsaturated lipids and oxidize them to lipid peroxides. This lipid peroxidation damage membrane protein as well as the lipids and thereby the integrity of membrane is lost. Therefore, it is considered that the extent of lipid peroxidation is directly proportional to cell damage. In addition, the free radicals may also attack DNA and causes tissue damage. Hyperlipidaemia is the greatest risk factor contributing to atherosclerosis & occurrence of coronary heart disease & cerebrovascular accidents. Hence hypolipidemic drugs are extensively used as prophylactic agents to prevent such atherosclerosis induced disorders. plants have been documented to have significant hypolipidemic actions. Based on these phytoconstituents the present is focused on review on antioxidant and antihyperlipidemic activities of Caesalpinia sappan bark. |
| Keywords: | Caesalpinia sappan, flavonoids, Anti-oxidant, Anti- hyperlipidaemic |
| Cite Article: | "A REVIEW ON ANTI-OXIDANT AND ANTIHYPERLIPIDEMIC ACTIVITES OF CAESALPINIA SAPPAN BARK.", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 10, page no.715-723, October-2022, Available :http://www.ijnrd.org/papers/IJNRD2210088.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2210088 Registration ID: 183490 Published In: Volume 7 Issue 10, October-2022 DOI (Digital Object Identifier): Page No: 715-723 Country: davanagere, karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2210088 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2210088 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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