Paper Title
FORMULATION AND EVALUATION OF TENOXICAM BUCCAL PATCHES FOR ARTHRITIC PAIN
Article Identifiers
Authors
Dr. Wajid Chaus. , Atiya shaikh , Rajesh Raut , Sneha Khandale , Priya Deshmukh
Keywords
Tenoxicam, Gelatin, sodium alginate, Chitosan, gum patches, Mucoadhesive drug delivery.
Abstract
The main objective of the present study was to improve the bioavailability of Tenoxicam and decrease the frequency of dosage form administration by mucoadhesive drug delivery system. Tenoxicam is an NSAIDS belonging to the class non selective cox-2 inhibitor, well known to cause gastrointestinal disorders and renal effects when given orally. A buccal patch for systemic administration of Tenoxicam in oral cavity were developed using polymers chitosan, sodium alginate, Gelatin, in order to deliver the drug to the particular region of the body for extended period of time, maximizing the drug availability, minimize the adverse effects, avoiding the first pass metabolism and thereby improving patient compliance. The formulated patches were evaluated for Mass uniformity and thickness uniformity, folding endurance, Drug content uniformity, Measurement of surface pH, Swelling index, Tensile strength, bioadhesion test, In vitro residence time, In vitro membrane permeation studies. Drug polymer compatibility studies were carried out by FTIR. & shows drug is compatible with polymers. The in vitro drug releases and in-vitro drug permeation studies showed that drug was released from the patches and permeated through the porcine buccal mucosa and hence the formulated buccal patches possibly permeate through the human buccal membrane also.
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How To Cite (APA)
Dr. Wajid Chaus., Atiya shaikh, Rajesh Raut , Sneha Khandale, & Priya Deshmukh (October-2022). FORMULATION AND EVALUATION OF TENOXICAM BUCCAL PATCHES FOR ARTHRITIC PAIN. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(10), 287-295. https://ijnrd.org/papers/IJNRD2210035.pdf
Issue
Volume 7 Issue 10, October-2022
Pages : 287-295
Other Publication Details
Paper Reg. ID: IJNRD_183372
Published Paper Id: IJNRD2210035
Downloads: 000121976
Research Area: Pharmacy
Country: Latur, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2210035.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2210035
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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Current Issue: Volume 10 | Issue 10 | October 2025
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