A review On Cubosomes and their Novel approches

A review On Cubosomes and their Novel approches

Registration ID: IJNRD_183130

Published ID: IJNRD2209177

DOI: Click Here to Get

P.Shailaja , Y.Samukhya , J.Ramya , K .Satya Ashok

Cubosomes, Honey combed structures, Bicontinuous cubic phase, Liquid crystals

Cubosomes are nanoparticles that primarily consist of specific amphiphilic lipids in a definite proportion and are stabilised by a polymer. They are known as bicontinuous cubic phase liquid crystals. cubosomes have tightly packed, twisted three-dimensional bilayers that resemble "honeycombed" formations and are thermodynamically stable. This honeycombed structure separates a large interfacial area and two internal aqueous channels. The term bicontinuous refers to the breakup of two continuous regions by lipid layer but non intersecting aqueous regions that is wicked into space filling structure. Cubosomes are formed by hydrating a surfactant or polar lipid that produces a cubic phase and then dispersing it into smaller particles. Cubosomes have high drug loading ability because of complex structure. They exhibit rheology like a solid. They have the capacity to encapsulate hydrophobic, hydrophilic, and amphiphilic materials. It enhances the solubility of poorly soluble drugs. These are Bio adhesive and biocompatible. They have various drug loading techniques and high internal surfaces. Other abilities of cubosomes are target and controlled release of bioactive agents. cubosome are versatile systems, administrable by different ways such as orally, percutaneously and parenterally, because of their properties. They are prepared by a simple method. cubosomes have high breaking resistance than liposomes. This article gives an overview on structure, preparation methods, evaluation and applications of cubosomes.

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"A review On Cubosomes and their Novel approches", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.7, Issue 9, page no.1502-1508, September-2022, Available :https://ijnrd.org/papers/IJNRD2209177.pdf

Volume 7 Issue 9, September-2022

Pages : 1502-1508

Paper Reg. ID: IJNRD_183130

Published Paper Id: IJNRD2209177

Downloads: 000121111

Research Area: Pharmacy

Country: Visakhapatnam, Andhra Pradesh, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2209177.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2209177

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

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