ANTIDIABETIC ACTIVITY OF ACACIA ARABICA LEAVES ON STREPTOZOTOCIN INDUCED RATS

ANTIDIABETIC ACTIVITY OF ACACIA ARABICA LEAVES ON STREPTOZOTOCIN INDUCED RATS

Registration ID: IJNRD_182618

Published ID: IJNRD2208135

DOI: Click Here to Get

Shubham K Marbade , Jugalkishor V Vyas , Vivek V Paithankar , Anjali M Wankhade , Janhavi Y Burade

Streptozotocin, acacia arabica, glibenclamide, hypoglycemia.

Diabetes mellitus (DM) is a major public health disorder affecting quite 400 million people worldwide. [1] It is group of common metabolic disorders that arising from variety of pathogenic mechanisms which are all results in high blood glucose level. Management of diabetes without any side effects is still a challenging for medical system which leads to an increasing search for improved antidiabetic drugs. The objective of this study was to evaluated antidiabetic activity of hydroalcoholic extract of Acacia arabica leaves. The hydroalcoholic extract of leaves of Acacia arabica were evaluated at different doses (100 mg/kg of body weight) for antidiabetic potential in streptozotocin induced rats. The extracts were administered for three weeks in different groups whereas glibenclamide (5 mg/kg body weight) was used as reference standard throughout study. All values are expressed as mean ± SEM. The differences were compared using one way analysis of variance (ANOVA) followed by Tukey Kramer Multiple comparison tests. P values < 0.05 were considered as significant. Chronic treatment with the hydroalcoholic extract of Acacia arabica at 100 and 200 mg/kg of body weight significantly (P < 0.001) causes decrease in blood glucose on 1ST, 7th, 14th and 21st day as shown in figure 1, 2, 3 and 4. The present investigation supports the hypoglycemic effects of extracts of ethnic folk medicine which mitigates pathological states like diabetes mellitus.

Published Paper   E-Certificate

"ANTIDIABETIC ACTIVITY OF ACACIA ARABICA LEAVES ON STREPTOZOTOCIN INDUCED RATS", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.7, Issue 8, page no.1236-1241, August-2022, Available :https://ijnrd.org/papers/IJNRD2208135.pdf

Volume 7 Issue 8, August-2022

Pages : 1236-1241

Paper Reg. ID: IJNRD_182618

Published Paper Id: IJNRD2208135

Downloads: 000121200

Research Area: Pharmacy

Country: Amravati, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2208135.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2208135

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition

Call For Paper - Volume 10 | Issue 8 | August 2025

IJNRD is Scholarly open access journals, Peer-reviewed, and Refereed Journals, High Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool), Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) with Open-Access Publications.

INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world. IJNRD will provide an opportunity for practitioners and educators of engineering field to exchange research evidence, models of best practice and innovative ideas.

Indexing In Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar | AI-Powered Research Tool, Microsoft Academic, Academia.edu, arXiv.org, Research Gate, CiteSeerX, ResearcherID Thomson Reuters, Mendeley : reference manager, DocStoc, ISSUU, Scribd, and many more

How to submit the paper?

Important Dates for Current issue

Paper Submission Open For: August 2025

Current Issue: Volume 10 | Issue 8

Last Date for Paper Submission: Till 31-Aug-2025

Notification of Review Result: Within 1-2 Days after Submitting paper.

Publication of Paper: Within 01-02 Days after Submititng documents.

Frequency: Monthly (12 issue Annually).

Journal Type: International Peer-reviewed, Refereed, and Open Access Journal.

Subject Category: Research Area