Paper Title
ANTIDIABETIC ACTIVITY OF ACACIA ARABICA LEAVES ON STREPTOZOTOCIN INDUCED RATS
Article Identifiers
Authors
Shubham K Marbade , Jugalkishor V Vyas , Vivek V Paithankar , Anjali M Wankhade , Janhavi Y Burade
Keywords
Streptozotocin, acacia arabica, glibenclamide, hypoglycemia.
Abstract
Diabetes mellitus (DM) is a major public health disorder affecting quite 400 million people worldwide. [1] It is group of common metabolic disorders that arising from variety of pathogenic mechanisms which are all results in high blood glucose level. Management of diabetes without any side effects is still a challenging for medical system which leads to an increasing search for improved antidiabetic drugs. The objective of this study was to evaluated antidiabetic activity of hydroalcoholic extract of Acacia arabica leaves. The hydroalcoholic extract of leaves of Acacia arabica were evaluated at different doses (100 mg/kg of body weight) for antidiabetic potential in streptozotocin induced rats. The extracts were administered for three weeks in different groups whereas glibenclamide (5 mg/kg body weight) was used as reference standard throughout study. All values are expressed as mean ± SEM. The differences were compared using one way analysis of variance (ANOVA) followed by Tukey Kramer Multiple comparison tests. P values < 0.05 were considered as significant. Chronic treatment with the hydroalcoholic extract of Acacia arabica at 100 and 200 mg/kg of body weight significantly (P < 0.001) causes decrease in blood glucose on 1ST, 7th, 14th and 21st day as shown in figure 1, 2, 3 and 4. The present investigation supports the hypoglycemic effects of extracts of ethnic folk medicine which mitigates pathological states like diabetes mellitus.
Downloads
How To Cite (APA)
Shubham K Marbade, Jugalkishor V Vyas, Vivek V Paithankar, Anjali M Wankhade, & Janhavi Y Burade (August-2022). ANTIDIABETIC ACTIVITY OF ACACIA ARABICA LEAVES ON STREPTOZOTOCIN INDUCED RATS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(8), 1236-1241. https://ijnrd.org/papers/IJNRD2208135.pdf
Issue
Volume 7 Issue 8, August-2022
Pages : 1236-1241
Other Publication Details
Paper Reg. ID: IJNRD_182618
Published Paper Id: IJNRD2208135
Downloads: 000121991
Research Area: Pharmacy
Country: Amravati, Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2208135.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2208135
About Publisher
Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG
Licence
This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
Publication Timeline
Article Preview: View Full Paper
Call For Paper
IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.
The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse fields. Its goal is to promote global scientific information exchange among researchers, developers, engineers, academicians, and practitioners. IJNRD serves as a platform where educators and professionals can share research evidence, models of best practice, and innovative ideas, contributing to academic growth and industry relevance.
Indexing Coverage includes Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many more recognized academic repositories.
How to submit the paper?
By Our website
Click Here to Submit Paper Online
Important Dates for Current issue
Paper Submission Open For: October 2025
Current Issue: Volume 10 | Issue 10 | October 2025
Impact Factor: 8.76
Last Date for Paper Submission: Till 31-Oct-2025
Notification of Review Result: Within 1-2 Days after Submitting paper.
Publication of Paper: Within 01-02 Days after Submititng documents.
Frequency: Monthly (12 issue Annually).
Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.
Subject Category: Research Area
Call for Paper: More Details
