INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Diabetes mellitus (DM) is a major public health disorder affecting quite 400 million people worldwide. [1] It is group of common metabolic disorders that arising from variety of pathogenic mechanisms which are all results in high blood glucose level. Management of diabetes without any side effects is still a challenging for medical system which leads to an increasing search for improved antidiabetic drugs. The objective of this study was to evaluated antidiabetic activity of hydroalcoholic extract of Acacia arabica leaves. The hydroalcoholic extract of leaves of Acacia arabica were evaluated at different doses (100 mg/kg of body weight) for antidiabetic potential in streptozotocin induced rats. The extracts were administered for three weeks in different groups whereas glibenclamide (5 mg/kg body weight) was used as reference standard throughout study. All values are expressed as mean ± SEM. The differences were compared using one way analysis of variance (ANOVA) followed by Tukey Kramer Multiple comparison tests. P values < 0.05 were considered as significant. Chronic treatment with the hydroalcoholic extract of Acacia arabica at 100 and 200 mg/kg of body weight significantly (P < 0.001) causes decrease in blood glucose on 1ST, 7th, 14th and 21st day as shown in figure 1, 2, 3 and 4. The present investigation supports the hypoglycemic effects of extracts of ethnic folk medicine which mitigates pathological states like diabetes mellitus.
"ANTIDIABETIC ACTIVITY OF ACACIA ARABICA LEAVES ON STREPTOZOTOCIN INDUCED RATS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 8, page no.1236-1241, August-2022, Available :http://www.ijnrd.org/papers/IJNRD2208135.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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