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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITIES 0F AGANOSMA CYMOS LEAVES IN STREPTOZOTOCIN INDUCED DIABETIC MICE |
| Authors Name: | Vishal Satish Patil , Ankita Bankhele , Rajesh J oswal |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_182583
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| Published Paper Id: | IJNRD2208122 |
| Published In: | Volume 7 Issue 8, August-2022 |
| DOI: | |
| Abstract: | ABSTRACT Diabetes mellitus (DM) is a systemic metabolic disorders with several major health complications affecting both the quality and the length of life. The purpose of this study is to appraise the antidiabetic and antihyperlipidemic activities of the Aganosma cymos leaves. Diabetes was induced in overnight fasted mice by a single intraperitoneal injection of Streptozotocin (60 mg/kg body weight) in a 0.1 M sodium citrate buffer (pH 4.5). The animals were divided into five groups with five animals in each and treated with methanolic extract of aganosma cymos leaves at dose 100 mg/kg and 200 mg/kg body weight respectively. The results showed that aganosma cymos leaves decrease blood glucose level significantly (p<0.001 to p<0.01) and also regulated parameters of lipid profile levels (TG, TC, LDL, VLDL, and HDL) significantly (p<0.001 to p<0.01) in experimental model of diabetes mellitus.levels of serum SGPT, SGOT and CRP were also adjusted to the normal level notably (p<0.001 to p<0.01) by the oral administration of methanolic extract of AGANOSMA CYMOS leaves (MACL). The results obtained from this study indicate that the methanolic extract of Aganosma cymos leaves contains bioactive substances with hypoglycemic potency. |
| Keywords: | KEYWORDS: Diabetes, Antidiabetic, Aganosma cymos, Lipid Profile. |
| Cite Article: | "HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITIES 0F AGANOSMA CYMOS LEAVES IN STREPTOZOTOCIN INDUCED DIABETIC MICE", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 8, page no.1121-1129, August-2022, Available :http://www.ijnrd.org/papers/IJNRD2208122.pdf |
| Downloads: | 000118751 |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2208122 Registration ID: 182583 Published In: Volume 7 Issue 8, August-2022 DOI (Digital Object Identifier): Page No: 1121-1129 Country: Pune, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2208122 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2208122 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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