Paper Title

HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITIES 0F AGANOSMA CYMOS LEAVES IN STREPTOZOTOCIN INDUCED DIABETIC MICE

Article Identifiers

Registration ID: IJNRD_182583

Published ID: IJNRD2208122

DOI: Click Here to Get

Authors

Vishal Satish Patil , Ankita Bankhele , Rajesh J oswal

Keywords

KEYWORDS: Diabetes, Antidiabetic, Aganosma cymos, Lipid Profile.

Abstract

ABSTRACT Diabetes mellitus (DM) is a systemic metabolic disorders with several major health complications affecting both the quality and the length of life. The purpose of this study is to appraise the antidiabetic and antihyperlipidemic activities of the Aganosma cymos leaves. Diabetes was induced in overnight fasted mice by a single intraperitoneal injection of Streptozotocin (60 mg/kg body weight) in a 0.1 M sodium citrate buffer (pH 4.5). The animals were divided into five groups with five animals in each and treated with methanolic extract of aganosma cymos leaves at dose 100 mg/kg and 200 mg/kg body weight respectively. The results showed that aganosma cymos leaves decrease blood glucose level significantly (p<0.001 to p<0.01) and also regulated parameters of lipid profile levels (TG, TC, LDL, VLDL, and HDL) significantly (p<0.001 to p<0.01) in experimental model of diabetes mellitus.levels of serum SGPT, SGOT and CRP were also adjusted to the normal level notably (p<0.001 to p<0.01) by the oral administration of methanolic extract of AGANOSMA CYMOS leaves (MACL). The results obtained from this study indicate that the methanolic extract of Aganosma cymos leaves contains bioactive substances with hypoglycemic potency.

How To Cite (APA)

Vishal Satish Patil, Ankita Bankhele, & Rajesh J oswal (August-2022). HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITIES 0F AGANOSMA CYMOS LEAVES IN STREPTOZOTOCIN INDUCED DIABETIC MICE. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(8), 1121-1129. https://ijnrd.org/papers/IJNRD2208122.pdf

Issue

Volume 7 Issue 8, August-2022

Pages : 1121-1129

Other Publication Details

Paper Reg. ID: IJNRD_182583

Published Paper Id: IJNRD2208122

Downloads: 000121984

Research Area: Pharmacy

Country: Pune, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2208122.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2208122

About Publisher

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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Call For Paper - Volume 10 | Issue 10 | October 2025

IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.

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Paper Submission Open For: October 2025

Current Issue: Volume 10 | Issue 10 | October 2025

Impact Factor: 8.76

Last Date for Paper Submission: Till 31-Oct-2025

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