AREVA LANATA (LINN.) JUSS.: AN ANTHELMINTIC HERB

Registration ID: IJNRD_182423

Published ID: IJNRD2208086

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Manjusha R. wath, Pritee M. Lande

Areva lanata, Anthelmintic, medicinal plants, earthworms and roundworms

ABSTRACTS: There is an increasing demand of herbal medicines globally, majority of herbs were used against different diseases. WHO estimated that two million of people harbour parasitic worm infection. Helminthes infections are one of the common health problems in India. These infections affect most population with major economic and social consequences. In view of this attempts have been made to study anthelmintic activity of A. lanata. The aerial parts of Areva lanata is widely used in the treatment of helminthiasis in folklore medicine. In this present study we investigated the folklore claim methodically and scientifically. The efficacy of plant extracts was proved by determining the time period for paralysis and death of earthworm and roundworm against different extracts (Acetone, chloroform, petroleum ether and aqueous) with different doses, i.e., 5, 15, 25, 50 and 75 mg/ml. Result revealed that Chloroform extract of A. lanata showed significant anthelmintic activity against Pheretima posthuma and Acetone extract for Haemonchus contortus than the standard drug. However, the efficacy of extracts was found to be considerably high at higher concentrations. For earthworm, standard drug at 75mg /ml showed paralysis at 3.75 ± 0.5 min and death time was 4.8 ± 0.8min and for Haemonchus contortus, standard drug at 75mg /ml showed paralysis at 3 ±0.8min and death time was 4.6 ± 1.6 min respectively. Among the various concentrations tested, Chloroform extract at 75mg/ml showed efficient paralytic effect at (4.6± 1.7 min) and death effect at (7.2±2 min) for Pheretima posthuma while Acetone extract at the same concentration found efficient for Haemonchus contortus paralytic effect at (1.8 ± 0.9min) and death effect at (2.8 ± 0.8min). Therefore, it may conclude from experimental evidences observed in this study A. lanata possesses significant anthelmintic properties and supports their use against intestinal helminths infections in traditional medicine.

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Manjusha R. wath & Pritee M. Lande (August-2022). AREVA LANATA (LINN.) JUSS.: AN ANTHELMINTIC HERB . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(8), 816-824. https://ijnrd.org/papers/IJNRD2208086.pdf

Volume 7 Issue 8, August-2022

Pages : 816-824

Paper Reg. ID: IJNRD_182423

Published Paper Id: IJNRD2208086

Downloads: 000122253

Research Area: Life Sciences 

Author Type: Indian Author

Country: Amravati, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2208086.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2208086

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