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ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
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Impact Factor : 8.76

Issue per Year : 12

Volume Published : 8

Issue Published : 85

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Authors Name: Shital B. Dhage , Sneha S. Tawani , Omprakash G. Bhusnure , Sachin B. Gholve , Padmaja S. Giram
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Published Paper Id: IJNRD2208006
Published In: Volume 7 Issue 8, August-2022
Abstract: Ankylosing spondylitis (AS) is an autoimmune, chronic inflammatory illness that mostly affects the spine, sacrum, and limb joints. The precise pathophysiology and causes of AS are still unknown as of this writing. The pathogenesis is thought to be influenced by genetic, environmental, immune, and other factors. The role of genetic variables in the development of AS has been the subject of the most extensive research among them. The role of epigenetic alteration and environmental predisposition in the pathogenesis of AS has received much interest in recent years. This article provides an overview of thea epigenetic alterations at genomic loci linked with ankylosing spondylitis, including DNA methylation, histone modification, and microRNA. In summary, this review's findings make an effort to explain how epigenetic alteration affects the occurrence and progression of AS. To further our understanding of the pathphysiology of AS, there are a number of unresolved and complex issues that require study.
Keywords: Ankylosing spondylitis, Epigenetic, Histone Modification, DNA Methylation, miRNA.
Cite Article: "HOLISTIC APPROACH RELATED TO ANKYLOSING SPONDYLITIS: A REVIEW", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 8, page no.36-49, August-2022, Available :http://www.ijnrd.org/papers/IJNRD2208006.pdf
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ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID:IJNRD2208006
Registration ID: 182310
Published In: Volume 7 Issue 8, August-2022
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Page No: 36-49
Country: Latur., Maharashtra, India
Research Area: Engineering
Publisher : IJ Publication
Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2208006
Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2208006
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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