Paper Title
HOLISTIC APPROACH RELATED TO ANKYLOSING SPONDYLITIS: A REVIEW
Article Identifiers
Keywords
Ankylosing spondylitis, Epigenetic, Histone Modification, DNA Methylation, miRNA.
Abstract
Ankylosing spondylitis (AS) is an autoimmune, chronic inflammatory illness that mostly affects the spine, sacrum, and limb joints. The precise pathophysiology and causes of AS are still unknown as of this writing. The pathogenesis is thought to be influenced by genetic, environmental, immune, and other factors. The role of genetic variables in the development of AS has been the subject of the most extensive research among them. The role of epigenetic alteration and environmental predisposition in the pathogenesis of AS has received much interest in recent years. This article provides an overview of thea epigenetic alterations at genomic loci linked with ankylosing spondylitis, including DNA methylation, histone modification, and microRNA. In summary, this review's findings make an effort to explain how epigenetic alteration affects the occurrence and progression of AS. To further our understanding of the pathphysiology of AS, there are a number of unresolved and complex issues that require study.
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How To Cite (APA)
Shital B. Dhage, Sneha S. Tawani, Omprakash G. Bhusnure, Sachin B. Gholve, & Padmaja S. Giram (August-2022). HOLISTIC APPROACH RELATED TO ANKYLOSING SPONDYLITIS: A REVIEW. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(8), 36-49. https://ijnrd.org/papers/IJNRD2208006.pdf
Issue
Volume 7 Issue 8, August-2022
Pages : 36-49
Other Publication Details
Paper Reg. ID: IJNRD_182310
Published Paper Id: IJNRD2208006
Downloads: 000122254
Research Area: Engineering
Author Type: Indian Author
Country: Latur., Maharashtra, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2208006.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2208006
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