Open Access
Research Paper
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Paper Title

HOLISTIC APPROACH RELATED TO ANKYLOSING SPONDYLITIS: A REVIEW

Article Identifiers

Registration ID: IJNRD_182310

Published ID: IJNRD2208006

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Keywords

Ankylosing spondylitis, Epigenetic, Histone Modification, DNA Methylation, miRNA.

Abstract

Ankylosing spondylitis (AS) is an autoimmune, chronic inflammatory illness that mostly affects the spine, sacrum, and limb joints. The precise pathophysiology and causes of AS are still unknown as of this writing. The pathogenesis is thought to be influenced by genetic, environmental, immune, and other factors. The role of genetic variables in the development of AS has been the subject of the most extensive research among them. The role of epigenetic alteration and environmental predisposition in the pathogenesis of AS has received much interest in recent years. This article provides an overview of thea epigenetic alterations at genomic loci linked with ankylosing spondylitis, including DNA methylation, histone modification, and microRNA. In summary, this review's findings make an effort to explain how epigenetic alteration affects the occurrence and progression of AS. To further our understanding of the pathphysiology of AS, there are a number of unresolved and complex issues that require study.

How To Cite (APA)

Shital B. Dhage, Sneha S. Tawani, Omprakash G. Bhusnure, Sachin B. Gholve, & Padmaja S. Giram (August-2022). HOLISTIC APPROACH RELATED TO ANKYLOSING SPONDYLITIS: A REVIEW. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(8), 36-49. https://ijnrd.org/papers/IJNRD2208006.pdf

Other Publication Details

Paper Reg. ID: IJNRD_182310

Published Paper Id: IJNRD2208006

Downloads: 000122254

Research Area: Engineering

Author Type: Indian Author

Country: Latur., Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2208006.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2208006

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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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Call For Paper - Volume 10 | Issue 12 | December 2025

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