Paper Title
Synthesis and Biological evaluation of new substituted imidazole and pyrazoles having Anti-microbial activity
Article Identifiers
Authors
Simranjeet Kaur , Manpreet Kaur , Amandeep Kaur , Monika Gupta , Namita Saini
Keywords
Antimicrobial activity, Imidazole, Pyrazole ,benzimidzole
Abstract
ABSTRACT In the current study, three compounds of 1-[1H-benzimidazole-1-yl-(phenyl)-methyl]-5-methyl-1,2-dihydro-2-(substituted)-3H-pyrazol-3-one derivatives were synthesized and biologically evaluated for in-vitro antimicrobial activity against gram negative bacteria Escherichia coli and gram positive bacteria Staphylococcus aureus. The purity of all synthesized compounds were tested by TLC and also identify structure by IR and 1H NMR spectroscopy. The all synthesized compounds have shown good to moderate antimicrobial activity against E. coli and S. aureus strains. Compound S1 show more zone of inhibition against gram negative bacteria and also S3 show more activity against gram positive bacteria.
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How To Cite (APA)
Simranjeet Kaur, Manpreet Kaur, Amandeep Kaur , Monika Gupta , & Namita Saini (July-2022). Synthesis and Biological evaluation of new substituted imidazole and pyrazoles having Anti-microbial activity . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(7), 1402-1407. https://ijnrd.org/papers/IJNRD2207158.pdf
Issue
Volume 7 Issue 7, July-2022
Pages : 1402-1407
Other Publication Details
Paper Reg. ID: IJNRD_182267
Published Paper Id: IJNRD2207158
Downloads: 000121982
Research Area: Pharmacy
Country: Morinda(Ropar), Punjab, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2207158.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2207158
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
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