Impact of Pathological stage on Locoregional Control of Carcinoma Breast cancer after adjuvant Treatment

Registration ID: IJNRD_182127

Published ID: IJNRD2207109

DOI: Click Here to Get

Poonam gupta

pathological stage ,local recurrence ,distant recurrence

Abstract Background- Although higher tumor stage is independent prognostic factors in carcinoma breast. The major risk factors for recurrence after mastectomy as initial therapy are the number of axillary lymph nodes positive at surgery in addition to other poor prognostic factors including younger age, higher-grade histology, receptor negative disease, and LVI. Risk factors for developing local recurrence after an initial breast-conserving approach are dictated mostly by margin status and receipt of radiotherapy. This study aimed to investigate the association of pathological stage with locoregional control. Material & Methods- This retrospective study was performed in 204 patients of carcinoma breast in Hanuman Prasad Poddar Cancer Hospital and Research Centre-Gorakhpur-India from 2018 to mid of 2022. Results¬-Out of 204 patients all were females except 2. Most of the patients had their age between 41-50 years and had stage III of disease. In hormone receptor status aspect maximum no of patients had ER(-) and PR(-) status. Out of 204patients 13(6.3%) patients developed local recurrence and 22(10.78%) patients developed distant metastasis. The patient who developed local failure or distant metastasis had one or more risk factors such as higher stage at presentation, many axillary node involvement in surgery,younger age or negative receptor status. Conclusions-The axillary nodal involvement, stage of disease at presentation and hormone receptor status are the important predictor of prognosis in carcinoma breast.

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Poonam gupta (July-2022). Impact of Pathological stage on Locoregional Control of Carcinoma Breast cancer after adjuvant Treatment . INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(7), 950-957. https://ijnrd.org/papers/IJNRD2207109.pdf

Volume 7 Issue 7, July-2022

Pages : 950-957

Paper Reg. ID: IJNRD_182127

Published Paper Id: IJNRD2207109

Downloads: 000121979

Research Area: Medical Science

Country: Gorakhpur, U.P, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2207109.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2207109

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

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