INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Dapagliflozin, a specific inhibitor of sodium-glucose co transporter 2 (SGLT2), prevents the kidney's proximal tubule from reabsorbing glucose and increases glucosuria. Dapagliflozin lowers renal glucose reabsorption by blocking the transporter protein SGLT2 in the kidneys, which causes urine glucose excretion and a drop in blood glucose levels. Dapagliflozin's effectiveness is independent of insulin secretion and action, in contrast to oral antidiabetic medications from numerous other groups. Inhibiting sodium-glucose cotransporter 2 (SGLT2) has recently become a key treatment approach for lowering cardiovascular risk in Type 2 DM. The probability of heart failure (HF) hospitalization has been found to be decreased by sodium-glucose co-transporter 2 (SGLT2) inhibitors in extensive clinical trials in individuals with type 2 diabetes who are at high cardiovascular risk. This favorable outcome was seen quickly after randomization, pointing to a mechanism or mechanisms of action distinct from those often taken into account with traditional glucose-lowering treatments
" Dapagliflozin: mechanism and safety in heart failure patients: A review", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 7, page no.480-485, July-2022, Available :http://www.ijnrd.org/papers/IJNRD2207060.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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