Paper Title
DEVELOPMENT AND FORMULATION OF POLYHERBAL OINTMENT AND EVALUATION OF ANTIOXIDANTS AND ANTIMICROBIAL POTENTIALS
Article Identifiers
Authors
Ms. Rajnandani Waskel , Mr. Kehar Singh Dhaker , Mrs. Sweety Tiwari , Dr. Akhlesh Kumar Singhai
Keywords
DEVELOPMENT AND FORMULATION OF POLYHERBAL OINTMENT AND EVALUATION OF ANTIOXIDANTS AND ANTIMICROBIAL POTENTIALS
Abstract
The objective of the present investigation was to formulate polyherbal ointment formulation for antioxidant and antibacterial action. Three plants Delonix regia leaves, Annona squamosa leaves and Curcuma longa rhizomes were used in the study and the methanolic extracts of the plant parts were used as the active ingredient of the ointments.The findings suggest the presence of alkaloids, glycosides, phenolics, terpenoids, proteins and flavonoids in the extracts. The total phenolic content in the extracts was determined using Folin-Ciocalteu method and was found to be 27.12, 31.57 and 22.36 GAE mg/g respectively.The polyherbal ointment formulations were prepared using simple ointment base and varying concentration of the DRE, ASE and CLE. The pH of all the formulations was almost equal to the pH of skin and ranged between 5.2 to 5.5. The spreadability value of the formulations revealed good spreading capacity.The antioxidant activity was determined using hydroxy radical scavenging assay method and reducing power assay method. It was found that formulation F2 was having highest antioxidant capacity of the three formulations in both the methods.The in vitro antibacterial action was determined using Staphylococcus aureus as the common bacterial strain utilizing disc diffusion method and the formulation F2 exhibited the highest zone of inhibition.
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How To Cite (APA)
Ms. Rajnandani Waskel, Mr. Kehar Singh Dhaker, Mrs. Sweety Tiwari, & Dr. Akhlesh Kumar Singhai (June-2022). DEVELOPMENT AND FORMULATION OF POLYHERBAL OINTMENT AND EVALUATION OF ANTIOXIDANTS AND ANTIMICROBIAL POTENTIALS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(6), 851-864. https://ijnrd.org/papers/IJNRD2206099.pdf
Issue
Volume 7 Issue 6, June-2022
Pages : 851-864
Other Publication Details
Paper Reg. ID: IJNRD_181881
Published Paper Id: IJNRD2206099
Downloads: 000121982
Research Area: Engineering
Country: -, -, -
Published Paper PDF: https://ijnrd.org/papers/IJNRD2206099.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2206099
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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
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