Paper Title
Visible Spectrophotometri determination of Valsartan in Pharmaceutical Formulations
Article Identifiers
Authors
Dr. K.Sandhyarani
Keywords
Spectrophotometry, Valsartan, ion-pair complex, Beer-Lambert's law,methylene blue, U.S. Pharmacopeia guidelines.
Abstract
A simple, rapid, sensitive, and accurate extractive spectrophotometric method has been developed for the determination of Valsartan in pure forms as well as their pharmaceutical dosage forms. The method depends on the formation of an intensely colored ion-pair complex between the acidic drug and methylene blue in alkaline medium The complex is stable and extractable into methylene chloride. All parameters were optimized. Beer-Lambert's law was obeyed in concentrations ranging from 0.5.-3.0 ml, 200 µg/ml. Statistical analysis of the calibration data was carried out, and correlation coefficients were in the range from 0.9996 to 0.9998. The developed method was fully validated according to International Conference on Harmonization guidelines, and complied with U.S. Pharmacopeia guidelines. The proposed method was applied to the analysis of the investigated drugs in their pharmaceutical formulations, and good recoveries were obtained. The results obtained were compared with those of reported and official methods, and no significant differences were found with t- and F-tests. The method is applied successfully for the estimation Valsartan in tablet form without the interference of excipients.
Downloads
How To Cite (APA)
Dr. K.Sandhyarani (June-2022). Visible Spectrophotometri determination of Valsartan in Pharmaceutical Formulations. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 7(6), 198-203. https://ijnrd.org/papers/IJNRD2206021.pdf
Issue
Volume 7 Issue 6, June-2022
Pages : 198-203
Other Publication Details
Paper Reg. ID: IJNRD_181569
Published Paper Id: IJNRD2206021
Downloads: 000121987
Research Area: Chemistry
Country: Vizianagaram, Andhrapradesh, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2206021.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2206021
About Publisher
Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJNRD (IJ Publication) Janvi Wave | IJNRD.ORG | IJNRD.COM | IJPUB.ORG
Licence
This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition
Publication Timeline
Article Preview: View Full Paper
Call For Paper
IJNRD is a Scholarly Open Access, Peer-reviewed, and Refereed Journal with a High Impact Factor of 8.76 (calculated by Google Scholar & Semantic Scholar | AI-Powered Research Tool). It is a Multidisciplinary, Monthly, Low-Cost Journal that follows UGC CARE 2025 Peer-Reviewed Journal Policy norms, Scopus journal standards, and Transparent Peer Review practices to ensure quality and credibility. IJNRD provides indexing in all major databases & metadata repositories, a citation generator, and Digital Object Identifier (DOI) for every published article with full open-access visibility.
The INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (IJNRD) aims to advance applied, theoretical, and experimental research across diverse fields. Its goal is to promote global scientific information exchange among researchers, developers, engineers, academicians, and practitioners. IJNRD serves as a platform where educators and professionals can share research evidence, models of best practice, and innovative ideas, contributing to academic growth and industry relevance.
Indexing Coverage includes Google Scholar, SSRN, ResearcherID-Publons, Semantic Scholar (AI-Powered Research Tool), Microsoft Academic, Academia.edu, arXiv.org, ResearchGate, CiteSeerX, ResearcherID (Thomson Reuters), Mendeley, DocStoc, ISSUU, Scribd, and many more recognized academic repositories.
How to submit the paper?
By Our website
Click Here to Submit Paper Online
Important Dates for Current issue
Paper Submission Open For: October 2025
Current Issue: Volume 10 | Issue 10 | October 2025
Impact Factor: 8.76
Last Date for Paper Submission: Till 31-Oct-2025
Notification of Review Result: Within 1-2 Days after Submitting paper.
Publication of Paper: Within 01-02 Days after Submititng documents.
Frequency: Monthly (12 issue Annually).
Journal Type: IJNRD is an International Peer-reviewed, Refereed, and Open Access Journal with Transparent Peer Review as per the new UGC CARE 2025 guidelines, offering low-cost multidisciplinary publication with Crossref DOI and global indexing.
Subject Category: Research Area
Call for Paper: More Details
