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IJNRD
INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
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Paper Title: Evaluation of antioxidant and antidiabetic activity of hydroalcoholic leaves extract of lagerstroemia floribunda
Authors Name: Mr. Sandeep Nayan Mishra , Dr. Manju Prajapati , Mrs. Sweeti Tiwari , Dr. Janki Prasad Rai , Dr. Akhlesh Kumar Singhai
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IJNRD_181639
Published Paper Id: IJNRD2205194
Published In: Volume 7 Issue 5, May-2022
DOI:
Abstract: Type 1 and type 2 diabetes mellitus is a serious and lifelong condition commonly characterised by abnormally elevated blood glucose levels due to a failure in insulin production or a decrease in insulin sensitivity and function. Over the years, prevalence of diabetes has increased globally and it is classified as one of the leading cause of high mortality and morbidity rate. Furthermore, diabetes confers a huge economic burden due to its management costs as well as its complications are skyrocketing. The conventional medications in diabetes treatment focusing on insulin secretion and insulin sensitisation cause unwanted side effects to patients and lead to incompliance as well as treatment failure. Besides insulin and oral hypoglycaemic agents, other treatments such as gene therapy and induced β-cells regeneration have not been widely introduced to manage diabetes. Secondary Plant constituents contain alkaloids, flavonoids, phenol, saponin, steroids and tannins. Medicinal plants have anticancer, antimicrobial, antidiabetic, antidiuretic and anti-inflammation activities. The increasing interest in powerful biological activity of secondary metabolites outlined the necessity of determining their contents in medicinal plants. In Indian Ayurvedic system, Lagerstroemia floribunda are well-known plants used for major and minor ailments. The aim of the present study is to examine leaf of Lagerstroemia floribunda for phytochemical profile, antioxidant potential and diabetic activity. Qualitative analysis of various phytochemical constituents and quantitative analysis of total phenolics and flavonoids were determined by the well-known test protocol available in the literature. Quantitative analysis of phenolic and flavonoids was carried out by FolinsCiocalteau reagent method and aluminium chloride method respectively. The findings of the present study will be helpful to phytochemists, pharmacologists and pharmaceutical industries.
Keywords: Lagerstroemia floribunda, Diabetes mellitus, β-cells, Antioxidant, Antidiabetic.
Cite Article: "Evaluation of antioxidant and antidiabetic activity of hydroalcoholic leaves extract of lagerstroemia floribunda", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 5, page no.1460-1475, May-2022, Available :http://www.ijnrd.org/papers/IJNRD2205194.pdf
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ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID:IJNRD2205194
Registration ID: 181639
Published In: Volume 7 Issue 5, May-2022
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Page No: 1460-1475
Country: -, -, India
Research Area: Engineering
Publisher : IJ Publication
Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2205194
Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2205194
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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