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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | A Review on:Solid Dispersion |
| Authors Name: | Nishigandha Nandkishor Dhokale , Yushra Shaikh , Pooja Shinde , Prasana Sisodya , Rahim Shaikh |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_180624
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| Published Paper Id: | IJNRD2203024 |
| Published In: | Volume 7 Issue 3, March-2022 |
| DOI: | |
| Abstract: | Solid dispersion ,defined as the dispersion of one or more active pharmaceutical ingredient in a carrier at solid state and an efficient technique to improve dissolution of purely water soluble drug to enhance their bioavailability .poor water solubility is one of the major problems for the various types of drugs and various approaches have been introduced for the inhancement of solubility of such drug the solubility behaviour of drug remains one of the most challenging aspects in formulation development . The number of poor water soluble compounds has dramatically increased . Currently only 10- 12% of new drug candidates have both high solubility and high permeability. More 60-65% of potent drug products suffer from poor water solubility solid dispersion have attracted considerable interest as an efficient means for improving the dissolution rate and hence the bioavailability of a range of hydrophobic drugs . Compared to conventional formulation such as tablets or capsules, solid dispersion which can be prepared by various methods have many advantages. Few of the aspects are to be considered for the preparation of solid dispersions, such as selection of carrier and methods of physicochemical characterisation. In this review , an over view on solid dispersions in general will be given with emphasis on the various types of the solid dispersions, manufacturing process, characterisation, advantages, disadvantages and the application of the solid dispersions, challenges in formulation of solid dispersion dosage forms, and various types of marketed preperations. |
| Keywords: | (Introduction, Solubilization enhancement Technique,Solid Dispersion,Method of Prepration) |
| Cite Article: | "A Review on:Solid Dispersion", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 3, page no.221-238, March-2022, Available :http://www.ijnrd.org/papers/IJNRD2203024.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2203024 Registration ID: 180624 Published In: Volume 7 Issue 3, March-2022 DOI (Digital Object Identifier): Page No: 221-238 Country: -, -, - Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2203024 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2203024 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016
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