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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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Volume 9 | Issue 5
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| Paper Title: | Comparing Mechanical Ventilation Duration Between Daily Sedation Interruption (DSI) And Protocolised Sedation On Critically Ill Adult Patients With Mechanical Ventilation Receiving Continuous Propofol |
| Authors Name: | Dr. Sudipa Das |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_214641
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| Published Paper Id: | IJNRD2403057 |
| Published In: | Volume 9 Issue 3, March-2024 |
| DOI: | |
| Abstract: | This study proposes a randomized controlled trial (RCT) comparing the efficacy of daily sedation interruption (DSI) versus protocolized sedation in adult patients requiring mechanical ventilation with continuous propofol infusion. The trial aims to address the gap in existing literature by focusing on non-benzodiazepine sedatives, which are preferred in current clinical practice. Conducted in six medical-surgical ICUs across the United Kingdom and Hong Kong, the RCT will enroll patients based on strict inclusion and exclusion criteria. Patients will be randomized to receive either DSI or protocolized sedation, with blinding of patients and data collectors. The primary outcome measure is the duration of mechanical ventilation, with secondary outcomes including ICU and hospital lengths of stay, level of wakefulness, unintentional device removal, and physical restraint use. Study anticipates enrolling approximately 200 patients per group to detect clinically significant differences in mechanical ventilation duration. This research aims to inform clinical practice and optimize sedation strategies for critically ill patients receiving mechanical ventilation. |
| Keywords: | Daily sedation interruption, Protocolized sedation, Nursing protocolized sedation, Nurse-led sedation, Nursing implemented sedation algorithm, Intermittent sedation, Intensive care unit ICU, Critical care, Mechanical ventilation-Ventilator, Invasive positive pressure ventilation(IPPV) |
| Cite Article: | "Comparing Mechanical Ventilation Duration Between Daily Sedation Interruption (DSI) And Protocolised Sedation On Critically Ill Adult Patients With Mechanical Ventilation Receiving Continuous Propofol", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 3, page no.a523-a533, March-2024, Available :http://www.ijnrd.org/papers/IJNRD2403057.pdf |
| Downloads: | 00065 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2403057 Registration ID: 214641 Published In: Volume 9 Issue 3, March-2024 DOI (Digital Object Identifier): Page No: a523-a533 Country: Kolkata, West Bengal, West Bengal, India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2403057 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2403057 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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