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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Decradation of Cerium oxide (CeO2) nanoparticles Absorption during Undamaged and Damaged Creature/Human Fur |
| Authors Name: | Dr. S R Chitra , Dr. M S Sameem , Mr. S S Saravanakumar , Mr. M Karthigeyan , Dr. R Ananthavalli |
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| Author Reg. ID: |
IJNRD_205402
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| Published Paper Id: | IJNRD2309206 |
| Published In: | Volume 8 Issue 9, September-2023 |
| DOI: | |
| Abstract: | Cerium oxide (CeO2) nanoparticles are used in polishing products and absorbents, as promoters in gash healing, and as organopesticide decontaminants. Whilst systemic bioaccumulation and organ toxicity has been portrayed after inhalation, data on CeO2 NPs’ transdermal permeation are lacking. Our study was an in vitro investigation of the permeation of 17-nm CeO2 nanoparticles dispersed in synthetic sweat (1 g L−1) using excised human skin on Franz cells. Experiments were performed using intact and needle-abraded skin, separately. The average amount of Ce into intact and damaged skin samples was 3.64 ± 0.15 and 7.07 ± 0.78 μg cm−2, respectively (mean ± SD, p = 0.04). Ce concentration in the receiving solution was 2.0 ± 0.4 and 3.3 ± 0.7 ng cm−2 after 24 h (p = 0.008). The Ce content was higher in dermal layers of damaged skin compared to intact skin (2.93 ± 0.71 μg cm−2 and 0.39 ± 0.16 μg cm−2, respectively; p = 0.004). Our data showed a very low dermal absorption and transdermal permeation of cerium, providing a first indication of Ce skin uptake due to contact with CeO2. |
| Keywords: | Franz cells; in vitro; cerium oxide nanoparticles; transdermal absorption |
| Cite Article: | "Decradation of Cerium oxide (CeO2) nanoparticles Absorption during Undamaged and Damaged Creature/Human Fur", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 9, page no.c68-c80, September-2023, Available :http://www.ijnrd.org/papers/IJNRD2309206.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2309206 Registration ID: 205402 Published In: Volume 8 Issue 9, September-2023 DOI (Digital Object Identifier): Page No: c68-c80 Country: -, -, India Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2309206 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2309206 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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