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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | PHYTOCHEMICAL SCREENING AND BIOLOICAL STUDIES OF Tetrataenium nepalense SEED EXTRACTS |
| Authors Name: | Rakshya Bantawa Rai , Dr. Sabyata Gautam , Rajan Manandhar , Mohan Pd. Amatya |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_218872
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| Published Paper Id: | IJNRD2404737 |
| Published In: | Volume 9 Issue 4, April-2024 |
| DOI: | http://doi.one/10.1729/Journal.39125 |
| Abstract: | Tetrataenium nepalense is a wild herb used traditionally to treat fever, common cold, cough etc. This plant takes three years to mature. The study investigates for antimicrobial, antifungal and antioxidant properties of Tetrataenium nepalense extract. This plant was extracted by maceration using ethanol. Then the percentage yield of extract was calculated. This plant was choose since it has historically been used to cure variety of ailments. The microscopic characteristics, extractive values and ash value of plant powder was done while UV spectrophotometry was used for the quantitative analysis, color change was the basis for the qualitative phytochemical screening. The extract contained phytochemicals such as alkaloids, steroids, quininone, coumarin, flavonoids, terpenoids, and carbohydrates, according to a preliminary phytochemical screening. The phenolic content was found to be 36.75 mg/g GAE and the flavonoid content was found to be 40.085 mg QE/g. The DPPH scavenging assay was carried out for antioxidant property and IC5O value was found to be 36.441379. During antibacterial screening, the extract was found to be effective against Bacillus subtilis and Staphylococcus aureus. This extract exhibited no antifungal action. For S. aureus, the minimum bactericidal concentration (MBC) was found to be between 25 and 50 mg/ml, while for Bacillius subtilis, it was found to be between 0.78125 and 1.5625 mg/ml. With its high quantity of total phenolic and total flavonoid content, the plant exhibits significant antioxidant activity. It also works well against gram-positive bacteria, which aids in the creation of narrow spectrum antibiotics. Therefore, this could be a potential lead molecule for antibiotics. Further research in Tetrataenium nepalense may lead to the discovery of the new molecule. |
| Keywords: | Tetrataenium nepalense, antibiotics, antioxidant, MBC |
| Cite Article: | "PHYTOCHEMICAL SCREENING AND BIOLOICAL STUDIES OF Tetrataenium nepalense SEED EXTRACTS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 4, page no.h302-h310, April-2024, Available :http://www.ijnrd.org/papers/IJNRD2404737.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2404737 Registration ID: 218872 Published In: Volume 9 Issue 4, April-2024 DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.39125 Page No: h302-h310 Country: -, -, India Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2404737 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2404737 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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